Fry has been a delivery boy for 1000 plus years. He is well known for his terrible work ethic, stupidity, and boyish charm.
Bender is a manbot that lives life in the fast lane. He relishes the finer things such as a nice drink, a classy cigar and killing all humans.
Leela is the hard-hitting one-eyed captain of the Planet Express ship. She has a complicated and emotional past full of failed love and mutants.
At 160 years old Professor Farnsworth is a renowned and senile inventor. His inventions have saved and almost destroyed the earth many times.